根据加纳和尼日利亚的高血压治疗状况发生中风:一个病例控制研究
Fred Stephen Sarfo1, Osahon Jeffery Asowata2, Onoja Matthew Akpa3
1Department of Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Journal of the neurological sciences
|March 22, 2024
概括
未经治疗和控制的高血压显著导致非洲中风. 改善高血压管理对于减少中风发病率和该地区的中风负担至关重要.
科学领域:
- 心血管流行病学心血管流行病学
- 公共卫生 公共卫生
- 脑卒中研究 脑卒中研究
背景情况:
- 高血压是中风的主要血管风险因素.
- 撒哈拉以南非洲地区正面临中风流行,原因是高血压意识,检测,治疗和控制不佳.
- 在该地区管理高血压方面存在重大差距.
研究的目的:
- 确定未经治疗,经过治疗但未得到控制和控制的高血压对加纳和尼日利亚中风发生的影响.
- 量化不同高血压管理状态对中风事件的可归因风险.
主要方法:
- 一项病例控制研究,即中风调查研究和教育网络 (SIREN),在加纳和尼日利亚的16个地点进行.
- 根据年龄和性别,急性中风病例 (n=3684) 与无中风对照 (n=3684) 相匹配.
- 使用调整的几率比率和人口归因风险,评估了高血压状态 (未治疗,未治疗,未治疗) 和中风风险之间的关联.
主要成果:
- 在中风病例中,高血压的发生率明显高于对照组 (p < 0.0001).
- 未经治疗的高血压 (aOR=6.58) 和接受治疗但未得到控制的高血压 (aOR=9.95) 与中风风险增加密切相关.
- 未经治疗的高血压占中风风险的35.4%,受治疗但未得到控制的高血压占中风风险的35.9%.
结论:
- 未经治疗和不充分控制的高血压在非洲土著人口中大大增加了中风发病率.
- 解决高血压预防和治疗差距的有针对性的干预措施至关重要.
- 社区,医疗保健提供者和政策制定者的协作努力可以减轻非洲日益增加的中风负担.
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