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发现了新型聚环神经氨基酶抑制剂,其中1,3,4-oxadiazole thioetheramide作为核心骨干

Lin Lin Shang1, Zhi Jian Zhong1, Li Ping Cheng1

  • 1School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China.

European journal of medicinal chemistry
|March 22, 2024
PubMed
概括

合成了新的多聚环神经氨基酶 (NA) 抑制剂. 化合物N5针对150腔和N10针对430腔,对分别野生型和突变型H5N1流感菌株表现出强大的活性.

关键词:
一百五十个洞穴430-洞穴的使用方式流感是一次流感.这是一种神经胺酶抑制剂.

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