PvGeneExpDB:一个整合性的基因表达数据库,以深入了解太平洋白 (Litopenaeus vannamei)
概括
我们开发了PvGeneExpDB,这是太平洋白 (Litopenaeus vannamei) 的第一个基因表达数据库. 本资源整合了转录基因数据,以提高对生物和水产养殖的理解.
科学领域:
- 水产养殖是水产养殖的一种方式.
- 基因组学就是基因组学.
- 生物信息学是一种生物信息学.
背景情况:
- 太平洋白 (Litopenaeus vannamei) 是一个重要的水产养殖物种.
- 转录组研究揭示了对生物学的洞察力,但数据是分散的.
- 为了全面分析的基因表达,需要一个集中的资源.
研究的目的:
- 建立PvGeneExpDB,这是第一个Litopenaeus vannamei.的综合基因表达数据库.
- 为分析各种生物条件的转录基因动态提供一个平台.
- 为了促进对太平洋白的更深入的生物学理解.
主要方法:
- 收集和分析了7个转录组数据集,包括53个样本.
- 进行了基因表达概况,差异表达和共同表达分析.
- 利用权重基因共同表达网络分析 (WGCNA) 进行大规模的共同表达分析.
主要成果:
- 建立了PvGeneExpDB,包括基因表达特征,差异表达和共同表达分析.
- 确定了20,599个新的转录,并分析了20,817个基因的表达特征.
- 成功地对76.7%的基因进行了基因本体学 (GO) 重建,并确定了26个新的共同表达的基因组.
结论:
- PvGeneExpDB为Litopenaeus vannamei研究提供了一个有价值的,综合的资源.
- 该数据库可以全面调查的转录基因动力学.
- 该资源将促进生物理解,并可能改善太平洋白的水产养殖实践.
相关概念视频
01:42What is Gene Expression?
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
02:11Reporter Genes
Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...
Commonly used reporter...