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Updated: Jun 27, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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Published on: April 9, 2014

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识别可点击的HIV-1囊向探针,用于病毒复制抑制

William M McFadden1, Mary C Casey-Moore2, Grant A L Bare3

  • 1Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive NE, Atlanta, GA 30322, USA; Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.

Cell chemical biology
|March 22, 2024
PubMed
概括

研究人员使用点击化学识别了HIV-1体蛋白 (CA) 的新型共价修饰剂. 一种化合物BBS-103通过与CA结合来破坏病毒的产生,为抗逆转录病毒药物开发提供了新的途径.

关键词:
艾滋病病毒-1 艾滋病病毒-1SuFEx SuFEx 是一个抗病毒屏幕的使用方法卡普西德 (Capsid) 是一种体.体向化合物 体向化合物然后点击化学.

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