儿童喘和过敏性疾病的关联因素使用隐性类分析
Teresa To1, Cornelia M Borkhoff2, Laura N Anderson3
1Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, 686 Bay St, Toronto, ON, M5G 0A4, Canada. teresa.to@sickkids.ca.
Scientific reports
|March 23, 2024
概括
来自不利背景的儿童面临着喘,过敏性鼻炎和湿疹的更高风险. 这些健康差异与通过隐性类分析 (LCA) 识别的特定的母婴集群有关,突出了社会经济和环境因素的影响.
科学领域:
- 儿科健康研究 儿科健康研究
- 流行病学 流行病学
- 健康的社会决定因素
背景情况:
- 来自贫困背景的儿童往往体验到更差的健康结果.
- 确定确定因素的集群对于了解早期儿童疾病风险至关重要.
- 纵向研究对于跟踪从出生开始的健康轨迹至关重要.
研究的目的:
- 通过隐性类分析 (LCA) 识别母婴决定因素的集群.
- 估计与这些集群相关的早期儿童疾病 (喘,过敏性鼻炎,湿疹) 的风险.
- 量化儿童医疗服务使用 (HSU) 与已识别的集群相关.
主要方法:
- 一个1993-2019年纵向队列研究,结合了三个加拿大儿科队列.
- 隐性类别分析 (LCA) 用于根据母,社会经济和环境领域的16个指标对母亲和儿童进行分类.
- 考克斯比例危险回归和Poisson回归用于量化疾病风险和医疗服务使用.
主要成果:
- 在15724对母婴对中,发现了四个不同的母婴群.
- 较年轻的母亲,移民/难民集群 (3和4类) 的母亲SES较低,环境暴露较差,与1类相比,他们的孩子患喘,过敏性鼻炎和湿疹的风险明显更高.
- 在3级过敏性鼻炎或湿疹的儿童中,医生和急诊室的访问增加.
结论:
- 隐性类分析有效地确定了与差异性健康结果相关的母婴群.
- 在特定集群中的不利的社会经济和环境因素与儿童过敏疾病的风险增加有关.
- 这些发现强调了解决儿科健康和医疗保健利用中的多因素决定因素的重要性.
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