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Updated: Jun 30, 2025

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae
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全球信号分析揭示了选择性Sec61抑制的原理

Nicole A Wenzell1, Brian B Tuch2, Dustin L McMinn2

  • 1Chemistry and Chemical Biology Program, University of California, San Francisco, San Francisco, CA, USA.

Nature chemical biology
|March 23, 2024
PubMed
概括

通过准Sec61转位子,cotransins抑制了蛋白质的产生. 研究人员开发了一个选平台,以识别对素敏感的特定信号 (SP),揭示基于序列的歧视机制.

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