在对癌症幸存者的基于人口的样本中,癌症诊断后使用大麻
Mimi Ton1,2, Polly A Newcomb1,2, Salene Jones1
1Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Avenue N, Seattle, WA, 98109, USA.
Cancer causes & control : CCC
|March 23, 2024
概括
近五分之二的癌症幸存者在诊断后使用大麻,通常用于睡眠,情绪或缓解疼痛. 这项研究强调了需要了解大麻的必要性.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 大麻素科学 大麻素科学
背景情况:
- 大麻使用在癌症患者和癌症幸存者中越来越普遍.
- 了解使用模式,方法和动机对于患者护理和研究至关重要.
- 华盛顿州提供了一个独特的环境,由于长期存在的合法娱乐和医用大麻市场.
研究的目的:
- 为了确定华盛顿州最近被诊断出癌症的癌症幸存者中大麻使用率.
- 确定该人口中大麻使用的方法和原因.
- 探索与诊断后大麻使用相关的相关性.
主要方法:
- 利用西雅图 - 普吉特湾监测,流行病学和最终结果 (SEER) 癌症登记册来识别在17个月内被诊断出癌症的癌症幸存者.
- 通过人口统计,病史和包括大麻在内的物质使用的问卷收集了1515名参与者的数据.
- 使用加权流行率估计和后勤回归来分析大麻使用模式和相关因素.
主要成果:
- 41.3%的癌症幸存者报告在诊断后使用大麻.
- 最常见的方法是食用 (60.5%) 和吸烟 (43.8%).
- 使用的主要原因包括睡眠 (54.5%),情绪/压力/焦虑/抑郁 (44.3%),疼痛 (42.3%) 和娱乐 (42.3%).
- 大麻使用与年龄较小,白人,教育程度较低,吸烟史,饮酒量较高,晚期癌症和特定癌症部位有关.
结论:
- 这是第一个基于大麻使用的基于人口的研究,在一个合法大麻州的多样化癌症幸存者群体中使用大麻.
- 大约五分之二的癌症幸存者报告在诊断后使用大麻.
- 进一步的研究对于调查大麻对癌症治疗结果和幸存者的健康影响至关重要.
相关概念视频
Cancer Survival Analysis
345
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
345
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
255
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
255
Psychoneuroimmunology: Diabetes and Cancer
28
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
Cancer Stem Cells and Tumor Maintenance
4.9K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
4.9K
Statistical Methods for Analyzing Epidemiological Data
364
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
364
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K


