在青少年和年轻成人癌症幸存者中,身体功能患者报告的结果:系统性审查
Sarah Tanner1, Teyl Engstrom1, Cheryl Forbes1
1Centre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.
Cancer medicine
|March 23, 2024
概括
与没有癌症的同龄人相比,患有癌症的青少年和年轻人 (AYA) 的身体功能和生活质量明显恶化. 需要进一步的纵向研究,以了解他们的长期康复和支持需求.
科学领域:
- 在瘤学瘤学.
- 康复医学 康复医学 康复医学
- 患者报告的结果
背景情况:
- 青少年和年轻人 (AYA) 在癌症诊断后面临着独特的身体挑战.
- 患者报告的结果测量 (PROM) 对于理解AYA癌症幸存者的经历至关重要.
- 在AYA中,生活质量 (QoL) 需要对身体功能进行专注的调查.
研究的目的:
- 为了比较AYA与癌症和非癌症对照之间的身体功能结果.
- 分析患者报告的癌症后AYA的身体功能数据.
主要方法:
- 对16项研究的系统审查,重点关注AYA中的身体功能PROM.
- 用EORTC-QLQ-C30进行身体功能评估的5项研究的元分析.
主要成果:
- 在16项研究中,有14项发现AYA癌症幸存者的身体功能明显恶化.
- 分析显示,癌症AYA患者的平均身体功能得分降低了7.03分.
- 身体功能的这种差异被认为具有临床意义.
结论:
- 被诊断患有癌症的AYA在身体功能方面表现出与健康相关的质量较差,而不是他们的无癌症同行.
- 这些结果强调,迫切需要解决AYA癌症幸存者的身体功能缺陷.
- 横截面研究的占主导地位表明,需要进行纵向研究,以跟踪AYA在整个癌症过程中.
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