外部固定和钉钉 (延长,然后钉钉) 的联合顺序使用中的分心骨质生成:在子上进行的一项实验研究
Elena A Shchepkina1, Leonid N Solomin1, Ivan V Lebedkov1
1Vreden Russian Research, Institute of Traumatology and Orthopedics, Ministry of Health of Russia, St. Petersburg, Russia.
概括
延长然后钉子 (LATN) 技术在子的小腿骨延长过程中促进了强大的周骨骨形成. 这种方法,与延长指甲 (LON) 一起,与传统方法相比没有缺陷.
科学领域:
- 整形外科手术 整形外科手术
- 再生医学是一种再生医学.
- 骨组织工程 骨组织工程
背景情况:
- 肢体延长利用分心骨质生成来进行骨再生.
- 延长然后钉 (LATN) 技术显示出增强周骨骨形成的希望,但需要实验验证.
- 了解骨再生机制对于改善肢体延长结果至关重要.
研究的目的:
- 用LATN技术比较使用子骨的分心骨质生成的组织再生与外部固定和延长指甲 (LON).
- 为了评估骨和内骨骨在骨延长期间的骨质形成.
- 确定LATN和LON技术在骨再生中的有效性.
主要方法:
- 在54只子身上进行了腿延长,分为三个组:外部固定器 (控制),LATN和LON.
- 放射学,计算机断层扫描和形态学研究是在45天多的多个时间点进行的.
- 用密度计分析来评估再生区域的骨密度.
主要成果:
- 与对照组相比,LATN和LON两组都表现出更明显的周骨骨形成.
- 通过LATN技术,可以获得宽的皮质板和最高的密度密度值.
- 在所有实验小组中,内骨骨形成保持不变.
结论:
- 与Ilizarov方法相比,LATN和LON技术不会影响分散骨质生成部位的组织再生.
- 外部固定后的钉钉 (LATN) 的顺序应用导致形成最坚固的骨结构.
- LATN和LON代表肢体延长的有效替代品,具有增强的骨再生潜力.
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