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Updated: May 12, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
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单细胞测序揭示了胸膜发育:了解胸膜上皮瘤的最新框架

Christopher S Nabel1,2,3, Jeanne B Ackman2,4, Yin P Hung2,5

  • 1Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

The oncologist
|March 23, 2024
PubMed
概括

胸膜上皮瘤 (TETs) 是罕见的,限制了治疗选择. 新的单细胞剖析揭示了对胸膜发育和TET的洞察力,为更好的治疗铺平了道路.

关键词:
一个单细胞RNA测序.胸腺癌 (thymic carcinoma) 是一种癌症.胸膜上皮瘤 胸膜上皮瘤蒂莫莫马马 (thymomaoma) 是一种疾病.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...