功能性发作的呼吸控制训练:一个多站点的开放标签试点研究.
Roderick Duncan1, David J Berlowitz2, Saul Mullen3
1Department of Neurology, Christchurch Hospital, Christchurch, New Zealand.
呼吸控制训练在治疗功能性发作方面表现有前途,这是一个缺乏有效治疗方法的疾病. 这项试点研究发现,许多参与者的发作频率有所改善,这表明了潜在的新型,具有成本效益的治疗方法.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 呼吸系统医学 呼吸系统医学
背景情况:
- 功能性 (FS) 缺乏经过充分验证的治疗方法,心理治疗的证据是合格的,并且访问有限.
- 高通风与功能性发作有关,这表明呼吸干预可能是有益的.
研究的目的:
- 探索呼吸控制训练作为功能性发作的新疗法.
- 评估FS的成年人呼吸控制训练的可行性,耐受性和初步有效性.
主要方法:
- 一个多站点,开放标签的试验试验,涉及18名功能性发作的成年参与者.
- 参与者接受了一小时的呼吸控制训练,由呼吸物理治疗师进行,然后一个月后进行30分钟的辅助训练.
- 发作频率和尼米根得分 (高通风度量) 在基线和干预后3-4个月被评估.
主要成果:
- 十名参与者完成了后续评估.
- 10名完成者中有7人表现出更好的发作频率 (p=0.09).
- 发作频率与尼米根得分有显著的相关性 (斯皮尔曼的rho=0.75,p=0.034),并且干预措施耐受良好,没有不良事件.
结论:
- 呼吸控制训练是管理功能性发作的潜在有效,成本效益和可接受的新方法.
- 这些初步发现需要通过随机对照试验进行确认,以确定最终的疗效.
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