在黑鱼的抗病毒天生的免疫力中,STAT2负面调节RIG-I

Ji Liu1, Chushan Dai2, Lijun Yin2

  • 1State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Science, Hunan Normal University, Changsha, 410081, China; College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410081, China.

PubMed
概括

黑鱼的STAT2通过抑制RIG-I无化来负面调节抗病毒免疫力. 这项研究揭示了脊椎动物先天免疫的新型机制,影响了模式识别受体信号传递.

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