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用自动心脏运动量计技术评估严重大动脉狭窄症患者的左心室功能

Jing He¹, Zi-Xin Yang², Wen-Long Zhang³

¹Department of Cardiovascular Ultrasonography, Central Hospital Affiliated To Shandong First Medical University, Jinan, China.

Ultrasound in medicine & biology

|March 23, 2024

概括

自动心肌运动量化 (aCMQ) 显示严重大动脉狭窄症 (SAS) 患者左心室功能受损. 这种技术可以识别定量标记来评估缩功能,即使在患有保留射出分数 (EF) 的患者中也是如此.

科学领域:

心脏病学心脏病学
医疗成像医学成像
心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

严重的大动脉狭窄 (SAS) 可能导致左心室 (LV) 缩功能发生改变.
在SAS患者中评估LV功能,特别是那些保持射出分数 (EF) ≥60%的患者,仍然具有挑战性.
需要定量标记器来精确评估SAS中的LV缩功能.

研究的目的:

用自动心肌运动量化 (aCMQ) 来探索SAS患者LV缩功能变化的研究.
确定可靠的定量标志物,以评估SAS患者的LV功能受损,EF≥60%.

主要方法:

七十名SAS患者 (按EF分类:≥60%,50-59%,<50%) 和30名对照人接受过胸腔心声扫描.
评估了传统的心声回声学参数.
自动心肌运动量化 (aCMQ) 软件分析了动态图像,以获得纵向峰值应变 (LPS) 参数.

主要成果:

与对照组相比,SAS组的上升性大动脉直径,左心脏直径,心室间隔膜厚度,左心室后壁厚度,缩速度峰值和平均压力梯度显著增加.
与对照组相比,SAS患者的纵向峰值应变 (LPS) 值明显较低.
左心室全球纵向缩峰值应变 (GLPS) 与平均压力梯度和E/A正相关,与大动脉面积指数负相关.

结论:

患有SAS和EF<50%的患者在LV心肌功能中表现出最严重的损伤.
aCMQ提供了精确的,定量评估LV缩功能损伤在SAS患者,包括那些保存EF (≥60%) 的患者.

关键词:

自动心脏运动量化技术自动心脏运动量化技术.心声回声扫描 (Echocardiography) 是一种心声回声扫描.左心室的缩功能左心室缩功能严重的大动脉狭窄症

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