随着时间的推移,从暂时全球性失忆症的症状开始,心率变化的变化
Soomi Cho1, Sue Hyun Lee2, Hye Jeong Lee3
1Department of Neurology, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Scientific reports
|March 24, 2024
概括
过渡性全球性失忆症 (TGA) 影响自主神经系统 (ANS) 功能,如心率变化 (HRV) 变化所示. HRV模式表明TGA后四周内恢复,这表明ANS功能正常化.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
背景情况:
- 过渡性全局性失忆症 (TGA) 往往先于与自主神经系统 (ANS) 功能障碍相关的事件.
- 心率变化 (HRV) 作为ANS状态和功能的关键指标.
研究的目的:
- 为了研究和描述TGA发作后HRV的时间变化.
- 为了比较TGA和健康对照后早期和晚期康复阶段的患者之间的HRV参数.
主要方法:
- 来自TGA患者的HRV数据的回顾性分析 (2015年1月 - 2020年5月).
- 时间域 (SDNN,RMSSD) 和频域HRV参数在三个组的比较:早期TGA (<1周),晚期TGA (1-4周) 和健康对照 (HC).
- 皮尔森的相关性分析,以评估时间后TGA和HRV参数之间的关系.
主要成果:
- 在早期TGA,晚期TGA和HC组中观察到时间域HRV参数的显著差异,特别是SDNN和RMSSD.
- 后期分析显示,早期和晚期TGA组之间SDNN和RMSSD的显著差异.
- 在频率域HRV参数 (总功率,LF,HF,LF/HF比率) 中没有发现跨组的显著差异.
- SDNN和RMSSD与TGA后的时间呈现负相关性,表明四周期间HRV指标下降.
结论:
- HRV参数,特别是时间域指标,如SDNN和RMSSD,在TGA之后随着时间的推移而动态变化.
- 由HRV反映的自主神经系统功能,似乎在TGA后四周内经历了初始变化和随后正常化的模式.
- 这些发现突显了HRV在监测过渡性全球性失忆症后恢复模式中的实用性.
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