在双胞胎早产婴儿中发生死性肠球炎的危险因素
Ying-Ling Xie1, Shu-Hua Lai1, Su-Jia Liu1
1Department of Neonatology, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
BMC pediatrics
|March 24, 2024
概括
先天性心脏病,对于妊娠年龄来说很小,以及出生窒息是双胞胎早产婴儿死性肠球炎 (NEC) 的关键危险因素. 对这些高风险新生儿来说,密切监测至关重要.
科学领域:
- 新生儿医学 新生儿医学
- 周围生理学 周围生理学
- 儿科手术 儿科手术
背景情况:
- 结核性肠球炎 (NEC) 是早产婴儿的严重胃肠道紧急情况.
- 双胞胎早产婴儿代表了一个独特的人群,对NEC的风险概况可能不同.
研究的目的:
- 为了确定与生死性肠球炎 (NEC) 在双胞胎早产婴儿的发展相关的重大风险因素.
- 在匹配的双胞胎早产婴儿队列中区分风险因素,有和没有NEC.
主要方法:
- 从67对双胞胎早产婴儿 (2010年1月至2021年12月) 的临床数据的回顾性分析.
- 根据NEC发生情况,婴儿被分为NEC (Bell II及以上) 和对照组.
- 进行了统计分析,包括单变量分析,以确定相关因素.
主要成果:
- 单变量分析显示,NEC和先天性心脏病 (CHD) 之间存在显著的关联.
- 怀孕年龄相对小 (SGA) 状态也是NEC的一个重要风险因素.
- 轻度出生窒息和食不耐受被确定为NEC发展的因素.
结论:
- 先天性心脏病,对于妊娠年龄来说很小,以及出生窒息是双胞胎早产婴儿中NEC的确诊危险因素.
- 积极的监测和管理策略对于出现心脏病,SGA或出生窒息的双胞胎早产婴儿至关重要.
- 早期识别和干预可以帮助最大限度地减少这种脆弱人群中NEC的发病率和严重程度.
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