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Updated: Jun 30, 2025

Evaluation of Caspase Activation to Assess Innate Immune Cell Death
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一种细菌毒素选择caspase-3来禁用活性气体皮质D,并限制巨细胞的热灭菌

Skylar S Wright1, Chengliang Wang1, Atri Ta2

  • 1Department of Immunology, UConn Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.

Cell reports
|March 24, 2024
PubMed
概括

肠出血性大肠杆菌 (EHEC) 使用Shiga毒素激活caspase-3,该毒素使气体皮质素D (GSDMD) 失活,并抑制热. 这揭示了一个新的细菌免疫逃避策略,针对活跃的GSDMD碎片.

关键词:
CP: 免疫学 免疫学CP: 微生物学 微生物学欧洲经济共同体 (EHEC) 是一个国家.石加毒素是一种毒素.卡斯酶-11是一种卡斯帕斯-3酶是什么意思肠道出血性大肠杆菌的发生.气体皮层 D D D D D这是一种非正规的炎症酶.热灭症是什么?

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