在COVID-19爆发后,日本的耳部疾病趋势:回顾性时间序列分析
Keisuke Kondo1, Keiji Honda2, Keiichi Goshima3
1Department of Health Policy and Informatics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, , S1651/S1568 M&D Tower, 1-5-45 Yushima, Bunkyo-ku, Tokyo 1138519, Japan; Department of Otorhinolaryngology, Tokyo Medical and Dental University, Tokyo, Japan.
Auris, nasus, larynx
|March 24, 2024
概括
冠状病毒病2019 (COVID-19) 和疫苗接种对面部神经麻和突然的感觉神经听力损失等耳部疾病的住院影响很小. 需要进一步的研究来证实这些发现.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19大流行和随后的疫苗接种活动引发了人们对它们对各种健康状况的潜在影响的担忧.
- 耳部疾病,包括面部神经麻,前庭神经炎,突然的感觉神经听力损失和梅尼尔病,由于潜在的神经和炎症途径,特别感兴趣.
研究的目的:
- 调查COVID-19流行病和COVID-19疫苗接种对特定耳部疾病住院率的影响.
- 评估COVID-19,疫苗接种和耳部疾病发病率之间的潜在因果关系.
主要方法:
- 使用日本大型住院患者数据库进行了追溯时间序列分析.
- 用因果影响算法和格兰杰因果测试来分析大流行前后和疫苗引入后的住院数据.
- 分析考虑了潜在的混因素,例如封锁措施.
主要成果:
- 因果影响分析显示,在COVID-19大流行开始后,因耳部疾病住院的病例没有显著增加.
- 对于这些疾病的住院率也显示在引入COVID-19疫苗后没有显著的激增.
- 格兰杰因果关系测试证实了因果影响分析的发现,表明缺乏显著的关联.
结论:
- COVID-19和疫苗似乎对主要耳部疾病的住院治疗产生了很小的影响.
- 这些发现表明,耳部病情可能不会受到大流行或疫苗接种努力的显著影响.
- 这些结果对公共卫生政策和流行病期间的医疗保健资源分配有影响,尽管建议进行长期监测.
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