传统中医与癌症的肠道微生物群之间的相互作用:目前的状况和未来的前景
Xuejiao Wei1, Fei Wang1, Peng Tan1
1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Pharmacological research
|March 24, 2024
概括
肠道微生物群影响癌症的发展和进展. 传统中国医学 (TCM) 调节肠道菌群,通过改变微生物组成和新陈代谢来增强抗瘤作用.
科学领域:
- 微生物学 微生物学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 肠道微生物群是一个复杂的微生态系统,在各种癌症 (结肠直肠,肝脏,胃,乳腺,肺) 中显著影响瘤的发展.
- 肠道菌群在癌症中起着双重作用,能够促进和抑制瘤的进展.
- 相互作用通过诸如肠肝轴,肺肠轴和免疫系统调节等机制发生.
研究的目的:
- 审查肠道菌群与主要癌症瘤发育之间的关联.
- 通过其与肠道微生物群的相互作用来检查传统中医 (TCM) 的抗瘤疗效.
- 确定研究缺口,并为未来关于TCM和癌症研究中的肠道微生物群的研究提供建议.
主要方法:
- 对肠道微生物群和癌症研究的文献综述.
- 对调查TCM对肠道菌群组成,结构和代谢物的影响的研究分析.
- 评估TCM对肠道屏障,免疫系统和宿主新陈代谢的影响.
主要成果:
- 肠道微生物群通过直接和间接的机制影响癌症的发展.
- TCM调节肠道菌群,影响宿主因素,并表现出显著的抗瘤作用.
- 肠道微生物群对TCM成分的代谢可以增强它们的抗瘤特性.
结论:
- TCM和肠道微生物群之间的相互作用为TCM的抗瘤机制提供了新的视角.
- 需要进一步的研究来充分阐明这些相互作用,并优化基于TCM的癌症疗法.
- 了解这种关系可以指导开发新的抗瘤药物和策略.
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