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在雄性动物中应激的繁殖毒性

Zikun Zhang1, Qi Wang1, Xiaoge Gao1

  • 1College of Life Sciences, Yan'an University, Yan'an, Shaanxi 716000, China; Yan'an Key Laboratory of Ecological Restoration, Yan'an, China.

Toxicology
|March 24, 2024
PubMed
概括

(Cd) 暴露会通过影响生殖细胞和HPG轴损害雄性动物的生殖能力. 这篇评论详细介绍了Cd的细节.

关键词:
是的组成部分.莱迪格细胞是莱迪格细胞.男人生育能力 男人生育能力甲基化 甲基化 甲基化叙事评审是对叙事进行的评审.塞尔托利细胞是什么?

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Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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