对BioFire®关节感染小组进行前性多中心评估,以快速记录急性关节炎的微生物学记录
Tiphaine Gaillard1, Céline Dupieux-Chabert1, Anne-Laure Roux2
1Hospices Civils de Lyon, Institut des Agents Infectieux, Laboratoire de Bactériologie, Hôpital Croix-Rousse, Lyon, France.
概括
生物Fire®关节感染面板 (BF-JIP) 准确检测急性关节炎的突液中的病原体. 这种快速检测显示出高性能,有助于及时诊断和治疗关节感染的决定.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 分子诊断学 分子诊断学
背景情况:
- 急性关节炎需要快速准确的诊断才能得到有效的治疗.
- 传统的方法,如膜液培养,可能会耗时.
- 识别抗生素耐药性基因对于指导治疗至关重要.
研究的目的:
- 评估BioFire®关节感染小组 (BF-JIP) 的诊断性能.
- 直接从突液中检测细菌和真菌病原体.
- 在急性关节炎患者中识别抗生素耐药性基因.
主要方法:
- 一项涉及六个法国实验室的多中心研究.
- 对308个疑似患有急性关节炎的患者的突液样本进行了测试.
- 将BF-JIP结果与14天的突液培养和其他分子方法进行比较.
主要成果:
- BF-JIP显示高一致性 (91.2%) 与14天培养.
- 积极的百分比协议为84.9%,100%的负面百分比协议.
- 积极的预测值为100%,而负的预测值为82.6%.
结论:
- 在急性关节炎中,BF-JIP对病原体检测具有很高的性能.
- 这种快速综合征面板有助于诊断关节感染.
- BF-JIP为及时识别致病原体提供了一个有价值的工具.
相关概念视频
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
434
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
434
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
842
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
842