在终极化疗放射治疗后,用于剩余食道瘤的内镜切除
Judith Honing1, Arjun D Koch1, Peter D Siersema1
1Department of Gastroenterology and Hepatology, Rotterdam MC Cancer Institute, University Medical Center Rotterdam, the Netherlands.
内镜切除提供了一个不那么侵入性的选择,在最终化学辐射 (CRT) 后早期食道癌复发. 这种方法在技术上取得了很高的成功,并且在精选的患者中是救援手术的可行替代方案.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 手术内镜是指手术内镜.
背景情况:
- 绝对化疗 (CRT) 是局部晚期,不可切除的食道癌症的标准.
- 经手术后的新辅助CRT是食道状细胞癌 (OSCC) 的替代方案.
- 确定CRT后的局部区域复发需要在符合条件的患者中进行救援治疗.
研究的目的:
- 审查食道癌早期复发的内镜治疗的临床结果和挑战.
- 评估内镜切除作为救援手术的不那么侵入性的替代方案.
主要方法:
- 审查一系列病例,证明最终CRT后内镜治疗结果.
- 分析技术成功率和临床结果.
- 在此背景下评估与内镜切除相关的挑战.
主要成果:
- 内镜切除已经证明在管理最终CRT后早期复发的技术成功率很高.
- 这种最少的侵入性方法是选择患者的传统救援手术的可行替代方案.
- 病例系列表明,在这种情况下,内镜治疗的结果很有希望.
结论:
- 内镜切除是一种可行的,不那么侵入性的治疗选择,用于在确定的化疗辐射后早期食道癌复发.
- 它为救援手术提供了一种有价值的替代方案,特别是在局限于粘膜或粘膜下层的瘤中.
- 进一步评估临床结果和优化技术是当前的挑战.
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