最大排泄体积和最大膀容量的比较,用于排泄日记,尿液流量计和囊泡计,用于非神经性下尿路功能障碍的儿童
Cagri Akin Sekerci1, Yiloren Tanidir2, Gunal Ozgur2
1Department of Urology, Division of Pediatric Urology, School of Medicine, Marmara University, Istanbul, Turkey.
Journal of pediatric urology
|March 24, 2024
概括
通过排空日记 (VD) 和尿液流量计 (UF) 测量的最大排空体积 (MVV) 是可比的. 然而,在患有下尿路功能障碍 (LUTD) 的儿童中,囊泡测量仪 (CMG) 的最大膀容量 (MBC) 较低.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 尿动力学 尿动力学 尿动力学
- 下尿道功能障碍 下尿道功能障碍
背景情况:
- 最大排泄体积 (MVV) 和最大膀容量 (MBC) 是评估儿科下尿路功能的关键指标.
- 在非神经性下尿路功能障碍 (LUTD) 的儿童中,这些测量在排泄日记 (VD),泌尿流量计 (UF) 和囊泡计 (CMG) 中的一致性需要进行具体的调查.
研究的目的:
- 为了比较VD和UF的MVV测量.
- 为了比较CMG的MBC测量.
- 确定导致非神经性LUTD儿童膀容量测量差异的因素.
主要方法:
- 对患有非神经性LUTD的儿童进行回顾性评估,重点关注VD,UF和CMG数据.
- 视频显示器被使用了2天来记录MVV (不包括第一个早晨的空白).
- 在预期膀容量 (EBC) <50%的儿童中重复UF;在特定条件下进行CMG,包括高排尿后残留尿 (PVR) 或耐火LUTD.
主要成果:
- 总共有54名儿童 (平均年龄10岁,72.2%的女孩) 进行了分析.
- 中位数MVV为232.50毫升 (VD) 和257.50毫升 (UF),而中位数MBC为184毫升 (CMG) (p=0.012).
- 在10岁以下的儿童,女孩,经常出现尿路感染的儿童,脱子过活,高PVR和正常流量模式中观察到膀容量测量的显著差异.
结论:
- 在患有非神经性LUTD的儿童中,从VD,UF和CMG测量膀容量之间存在差异.
- 在CMG中较低的MBC值可能源于在侵入性手术期间患者的服从性降低.
- 建议将CMG发现与VD,UF和临床数据进行整合,以防止儿科LUTD的错误诊断和过度治疗.
相关概念视频
Renal Clearance
930
The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
930
Determination of Renal Drug Clearance: Graphical and Midpoint Methods
114
Renal clearance, a crucial parameter in pharmacokinetics, can be determined using two different methods: the graphical method and the midpoint method. These methods provide insights into the rate of drug excretion by the kidneys and aid in assessing renal function.
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
114
Urinary Bladder
660
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
660
Factors Affecting Renal Clearance: Renal Impairment
91
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
91


