关于带有神经内分泌特征的尿囊瘤的最新情况
Dilara Akbulut1, Hikmat Al-Ahmadie2
1Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD.
Advances in anatomic pathology
|March 25, 2024
概括
小细胞癌是最常见的膀神经内分泌瘤. 分子特征学的进步正在改善罕见的膀神经内分泌瘤的分类和理解.
科学领域:
- 泌尿外科瘤学 泌尿外科瘤学
- 病理学 病理学 病理学
- 分子诊断学 分子诊断学
背景情况:
- 小细胞癌是尿道膀最常见的神经内分泌瘤,以纯或混合亚型出现.
- 膀的大细胞神经内分泌癌是不常见的,不清楚定义,尽管越来越多地承认.
- 区分良好的神经内分泌瘤和横瘤是极其罕见的膀瘤.
研究的目的:
- 审查膀神经内分泌瘤的分类和特征.
- 为了突出最近在分子表征方面取得的进展,以改善瘤分层.
主要方法:
- 关于膀神经内分泌瘤的文献综述.
- 对最近的分子发现和分类系统的分析.
主要成果:
- 小细胞癌是主要的亚型.
- 大细胞神经内分泌癌被认为是一个独特的实体.
- 分子进步正在提高诊断准确性和治疗潜力.
结论:
- 膀的神经内分泌瘤包括一系列罕见的恶性瘤.
- 分子分析对于准确的分类和未来的治疗策略至关重要.
相关概念视频
Urinary Bladder
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Anatomy of the Genitourinary System II: Bladder and Urethra
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...


