一个罕见的持续多焦点形状甲状腺癌的罕见病例
William Kuenstner1, Po Zhao1, Wen Lee2
1MedStar Georgetown University Hospital, Washington, D.C.
AACE clinical case reports
|March 25, 2024
概括
状状甲状腺癌 (CMTC) 是一种与家族性腺瘤多重症 (FAP) 相关的独特实体. 早期识别和基因检测对于管理CMTC和FAP患者至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- 现在,根据2022年世卫组织分类,状状甲状腺癌 (CMTC) 已被视为一个独立的实体,与乳头状甲状腺癌 (PTC) 不同.
- CMTC与家族腺瘤多重症 (FAP) 有着已知的关联,这是一种导致结直肠癌的遗传性疾病.
研究的目的:
- 在后来被诊断为FAP的患者中报告CMTC病例.
- 强调这些条件及其管理影响之间的联系.
主要方法:
- 一个15岁的女性呈现出,消化不良和胃肠道症状.
- 诊断工作包括甲状腺超声波,细针吸收活检和基因检测.
- 手术管理涉及全甲状腺切除术与辅助放射性治疗.
主要成果:
- 最初的活检表明PTC,但经过甲状腺切除术后的修订诊断是多焦点CMTC.
- 基因检测证实了该患者的FAP.
- 患者被转诊进行进一步的胃肠道评估和潜在的切除术.
结论:
- 患有结直肠癌的家族史应该引起CMTC的怀疑.
- 诊断为CMTC的患者需要转诊进行结肠镜检查和FAP遗传检测.
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