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视神经膜脑膜瘤的放射治疗:局部控制和治疗相关的视觉变化
Jorge Alejandro Torres-Ríos1, Alejandro Rodríguez-Camacho1,2, Estefania Basilio-Tomé1
1Radioneurosurgery Unit, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Mexico City, 14269, Mexico.
World neurosurgery: X
|March 25, 2024
概括
电离辐射有效控制视神经外脑膜瘤 (ONSMs),但可能导致视力丧失. 虽然生存率很好,但在接受放射治疗的ONSM患者中,视觉预后仍然很差.
科学领域:
- 神经外科 神经外科
- 辐射瘤学 辐射瘤学
- 眼科医生 眼科 眼科
背景情况:
- 视神经膜膜膜瘤 (ONSMs) 是一种影响视神经的罕见瘤.
- 对ONSM的治疗选择包括观察,手术和放射治疗.
研究的目的:
- 评估用电离辐射治疗的ONSM的局部控制.
- 评估ONSM治疗后的视觉变化和功能状态.
主要方法:
- 在2016年至2022年期间,对19名接受电离辐射治疗的患者进行了回顾性分析.
- 分析了眼科随访,发病率和生存数据.
主要成果:
- 无进展生存 (PFS) 的中位数为60个月,48个月的PFS为100%.
- 在诊断时,47.3%的眼睛有黄斑病;在那些有视力的人中,70%的人经历了治疗后视力敏度的下降.
- 在第一年内,有3名患者出现了黄斑病 (p=0.018).
结论:
- 电离辐射治疗对于局部ONSM控制是成功的.
- 辐射可以损害视觉敏度,但可以改善其他视觉缺陷.
- ONSM患者的生命预后良好,但视觉预后不佳.
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