多胎妊娠对希腊死产的贡献:时间趋势分析
Nikolaos Vlachadis1, Sofoklis Stavros2, Nikolaos Machairiotis2
1Department of Obstetrics and Gynecology, General Hospital of Messinia, Kalamata, GRC.
Cureus
|March 25, 2024
概括
多胎妊娠在希腊显著增加死胎的风险. 虽然最近死胎率有所下降,但多胎妊娠仍然存在相当大的风险,需要针对性干预以改善围产期结果.
科学领域:
- 围产期流行病学 围产期流行病学
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 多胎妊娠是已知的胎儿死亡风险因素.
- 了解对死产率的影响对于公共卫生倡议至关重要.
研究的目的:
- 检查多胎妊娠对希腊人口中死产率 (SBR) 的影响.
- 分析SBR和人口归因风险 (PAR) 的时间趋势,用于与多胎妊娠相关的死产.
主要方法:
- 利用希腊统计局65年 (1957-2021) 的活产和死产数据.
- 计算多胎和单胎妊娠的SBR,以及可归因于多胎妊娠的PAR (%).
- 通过结合点回归分析评估时间趋势.
主要成果:
- 在希腊 (1957-2021年),多胎孕占死胎总数的9.4%,胎儿死亡的相对风险比单胎高3.34倍.
- 多胎产生的SBR在1976年之前保持稳定,然后下降 (APC = -3.0).
- PAR (%) 从1975-2011年增加 (APC = 3.4),但从2011-2021年大幅下降 (APC = -6.1),从19.3%下降到8.6%.
结论:
- 多胎妊娠在希腊显著影响死胎率.
- 多胎妊娠中SBR和PAR (%) 的最近下降趋势令人鼓舞.
- 进一步的有针对性的干预措施是必要的,以提高在多胎妊娠中围产期的结果.
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