牙周炎和炎症性肠病:一篇综述
Faris I Ozayzan1, Amal A Albishri2, Abdulaziz E Dallak3
1Dentistry, Ministry of Health, Jazan, SAU.
Cureus
|March 25, 2024
概括
牙周炎 (PD) 和炎症性肠病 (IBD) 显示出一种复杂的关系,可能由口腔肠轴介导. 研究表明存在联系,但需要更多的研究来确认机制和临床相关性.
科学领域:
- 口腔健康和胃肠道学
- 微生物组研究 微生物组研究
- 免疫学 免疫学 免疫学
背景情况:
- 牙周炎 (PD) 和炎症性肠病 (IBD) 是慢性炎症性疾病.
- 最近的研究强调了口腔肠轴在它们的相互作用中的潜在作用.
- 了解这种联系对于开发有效治疗方法至关重要.
研究的目的:
- 对有关牙周炎和炎症性肠病之间的关系的研究进行全面审查.
- 分析2003年至2023年间发表的研究.
- 作为未来对口腔肠轴的研究的参考.
主要方法:
- 在PubMed数据库中使用关键词"牙周炎"和"炎症性肠病"进行文献搜索.
- 手动的图书馆搜索和对文献的审查.
- 在297篇获取的文章中,选择和分析了27篇相关研究.
主要成果:
- 在78%的审查研究中发现牙周炎和炎症性肠病之间存在显著的关联.
- 在许多情况下,这种关系似乎是双向的,尽管一些研究驳斥或质疑其临床相关性.
- 有证据表明,口腔肠轴在调解这种连接方面发挥着关键作用.
结论:
- 牙周炎和炎症性肠病之间的联系得到了大多数最近的研究的支持.
- 需要进一步进行高质量的研究,包括随机试验,以阐明分子机制和临床影响.
- 调查影响结果的因素对于澄清复杂的口腔-肠道疾病相互作用至关重要.
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