甲状腺切除术对体重指数和甲状腺刺激激素的影响:系统性审查和元分析
Hyder Mirghani1, Ahmad M Fnjan2, Abdullah F Almalki1
1Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
Cureus
|March 25, 2024
概括
这次元分析发现甲状腺切除术后体重或体重指数 (BMI) 没有显著变化. 该研究分析了六篇研究论文,得出结论,甲状腺手术不会影响体重或BMI.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 代谢健康 代谢健康
背景情况:
- 甲状腺切除术是治疗各种甲状腺疾病的常见外科手术,包括癌症,,甲状腺功能障碍等.
- 甲状腺切除术对术后体重和体重指数 (BMI) 的影响仍然是争论的主题.
- 了解这些变化对于患者管理和长期健康结果至关重要.
研究的目的:
- 进行元分析,评估甲状腺切除术与随后的体重和BMI变化之间的关系.
- 从现有文献中综合证据,以更清楚地了解甲状腺切除术后的体重波动.
- 调查甲状腺切除术指示与体重变化之间的潜在关联.
主要方法:
- 在PubMed,Medline和谷歌学者中进行了系统的文献搜索,直到2024年1月.
- 包括专注于全额或部分全额甲状腺切除术和评估体重和BMI的研究.
- 六项研究 (五项追溯,一项前性) 符合元分析的纳入标准.
主要成果:
- 甲状腺切除术前后的元分析没有显示出体重或BMI在甲状腺切除术前后的统计学上显著差异.
- 统计分析显示,对体重 (OR: -0.63,P=0.15) 或BMI (OR: -0.12,P=0.40) 没有显著影响.
- 在包括的研究中没有观察到异质性 (I2=0.0%),表明结果一致.
结论:
- 甲状腺切除术,无论是针对差异化甲状腺癌还是甲状腺功能障碍症,似乎都与体重或BMI的显著变化无关.
- 需要进一步的研究来探索甲状腺刺激激素 (TSH) 水平,放射性治疗和甲状腺素剂量在甲状腺切除术后代谢变化中的作用.
- 目前的证据表明,甲状腺切除术后的体重管理可能不需要仅仅基于手术本身的具体调整.
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