克拉诱发的精神失调和偏执妄想
Matthew Awad1, Hugh H Burke1, Scott A Oakman2
1Department of Psychiatry & Behavioral Sciences, University of Minnesota Medical School - Twin Cities, Minneapolis, USA.
Cureus
|March 25, 2024
概括
克拉是一种植物提取物,可能会在患有先前精神健康状况的人中引发新的精神病症状,如偏执. 这一案例凸显了与 kratom 使用相关的潜在精神病风险.
科学领域:
- 精神病学是一个精神病学.
- 毒理学 毒理学 毒理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 克拉 (Mitragyna speciosa) 是一种原产于东南亚的热带树,其叶子含有精神活性化合物.
- 由于其兴奋剂和类似阿片类药物的作用,在美国越来越多地使用它,尽管对其长期影响的理解有限.
- Kratom 使用与滥用和罕见但严重的不良事件的可能性有关.
研究的目的:
- 报告一种可能因 kratom 使用而引起的急性精神失补偿病例.
- 为了研究加大kratom消费和新型精神病症状之间的关联,在一个有精神分裂情绪障碍病史的患者.
主要方法:
- 一个患有双极性精神分裂情绪障碍的患者的病例报告.
- 审查患者的精神病史和最近的物质使用情况.
- 临床评估急性开始的偏执和妄想.
主要成果:
- 患者出现了新的偏执和妄想,与之前的精神病发作不同.
- 这位患者在精神病失补偿之前一直在摄入越来越多的kratom.
- 在之前的住院治疗中,没有注意到偏执狂妄想思想内容的前史.
结论:
- 在易受影响的个体中,使用Kratom可能会导致急性精神病症状,包括偏执和妄想.
- 这一案例表明了kratom摄入和精神疾病恶化之间的潜在联系.
- 进一步的研究是有必要的,以了解克拉诱导精神病的神经生物学机制和临床影响.
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