身体炼频率和认知:一个多中心的横截面队列研究
Chen Wen1, Jing-Huan Gan2, Guo-Wei Huang3
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China.
定期体育炼 (PE) 与老年人的痴呆风险降低和认知能力改善有关. 对于大多数人来说,每周炼三次或更多次是最优的,而对于没有高血压的人来说,一到两次会有好处.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 痴呆症是一个重大的社会和家庭负担.
- 有效的预防策略和痴呆症治疗非常重要.
- 了解生活方式因素的作用,如体育炼,对于预防痴呆症至关重要.
研究的目的:
- 研究中国老年人体育炼 (PE) 频率与认知功能之间的关联.
- 为预防痴呆和认知健康建立最佳的体育炼频率.
- 探索不同痴呆症亚型和人口群体之间的这些关联.
主要方法:
- 这是一项大规模的研究,涉及16,181名65岁及以上的中国参与者.
- 使用多变量逻辑和线性回归分析来评估PE频率与认知之间的关系.
- 进行了跨痴呆症亚型,年龄组和中风或高血压或没有中风或高血压的个体的子组分析.
主要成果:
- 身体炼与痴呆症风险降低有显著关联 (OR:0.5414,p < 0.001).
- 每周运动三次或更多次与较低的痴呆风险有很强的关联 (OR:0.4794-0.6619,所有p<0.001).
- 任何PE的频率都与认知能力的改善有关 (β: 12851,p < 0.001),观察到至少每周一次运动有显著的益处 (p < 0.001).
- 没有高血压的个体在认知上受益于每周1-2次炼 (OR:0.6168,p = 0.005).
结论:
- 建议每周炼三次或更多次,作为不同痴呆症亚型和年龄组的个体的最佳频率.
- 对于没有高血压的人来说,每周1-2次进行体育炼也显示出认知效益.
- 这些发现强调了定期体育活动对于保持认知健康和预防老年痴呆症的重要性.
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