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适应的糖尿病并发症严重程度指数预测了老龄化2型糖尿病患者的痴呆风险

Mingyang Sun¹, Wan-Ming Chen^2,3, Szu-Yuan Wu^{2,3,4,5,6,7,8,9,10}

¹Department of Anesthesiology and Perioperative Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, 450052, China.

Brain communications

|March 25, 2024

概括

在2型糖尿病诊断时,适应的糖尿病并发症严重性指数 (aDCSi) 与老年患者的痴呆风险更高有关. 较高的aDCSi得分表明患痴呆症的可能性增加,强调积极的糖尿病管理.

科学领域:

老年学是一门学科.
内分泌学在内分泌学.
神经学神经学

背景情况:

2型糖尿病 (T2DM) 是老年人中普遍存在的慢性疾病.
糖尿病与认知能力下降和痴呆症的风险增加有关.
早期识别T2DM患者痴呆的危险因素至关重要.

研究的目的:

调查T2DM诊断时适应的糖尿病并发症严重性指数 (aDCSi) 与老年患者痴呆风险之间的关联.
为了确定在诊断时糖尿病并发症的严重程度是否可以预测未来的痴呆风险.

主要方法:

分析了一大批老年T2DM患者 (年龄≥60岁).
倾向性得分匹配用于控制混因素.
使用考克斯回归和卡普兰-梅尔方法来评估痴呆风险和累积发病率.

主要成果:

诊断时aDCSi得分为1或更高的患者患痴呆的风险明显更高 (调整后的危险比:1.30).
痴呆症风险随着aDCSi得分的提高而逐渐增加,每分增加1.17倍.
aDCSi与痴呆风险之间的关联是统计学上显著的 (P < 0.0001).

结论:

在T2DM诊断时,较高的aDCSi得分是老年人痴呆风险升高的重要预测因素.
aDCSi可以作为一种有价值的工具,用于识别患有痴呆症高风险的老年T2DM患者.
有效地管理糖尿病并发症对于减轻这种脆弱人群中痴呆风险至关重要.

关键词:

这就是T2DM.一个DCSI一个DCSI.与糖尿病相关的痴呆症.年老的年龄-年老的年龄.预测性预测性预测性

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