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Updated: Jun 29, 2025

An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics
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稳定的5'帽类比物用于光化学激活mRNA翻译

Florian P Weissenboeck1, Nils Klöcker1, Petr Špaček1

  • 1Institute of Biochemistry, University of Münster, Münster 48149, Germany.

ACS omega
|March 25, 2024
PubMed
概括

科学家们设计了一种新型的可光激活的5'盖模拟物Medronate-FlashCap,用于精确控制mRNA翻译和稳定性. 光激活使得可调节的蛋白质产生和抵抗分解酶的降解.

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