相关实验视频
Updated: Jul 5, 2026

05:57
Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases
Published on: August 2, 2022
4.1K
史蒂文斯-约翰逊综合征/有毒表皮解的双等离子体分子吸附系统:一个病例报告
You-Wen Tan1, Li-Ping Liu2, Kai Zhang2
1Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212003, Jiangsu Province, China. tyw915@sina.com.
World journal of clinical cases
|March 25, 2024
概括
双等离子体分子吸附系统 (DPMAS) 疗法在COVID-19患者中有效治疗了史蒂文斯-约翰逊综合征和有毒表皮解 (SJS/TEN). DPMAS减少了炎症媒介,解决了严重的皮肤反应.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 史蒂文斯-约翰逊综合征 (SJS) 和有毒表皮解体 (TEN) 是严重的皮肤不良反应.
- 病因包括感染和药物;SARS-CoV-2是潜在的触发因素.
- 与COVID-19相关的SJS/TEN需要有效的治疗策略.
研究的目的:
- 在COVID-19之后报告SJS/TEN病例.
- 评估双等离子分子吸附系统 (DPMAS) 治疗在SJS/TEN.管理中的疗效.
- 探索DPMAS在减少SJS/TEN中的炎症介质中的作用.
主要方法:
- 一份关于一个三十多岁的女性的病例报告,她在COVID-19和乙氨基使用后发展了SJS/TEN.
- 最初用皮质类固醇治疗是无效的.
- 双重血分子吸附系统 (DPMAS) 治疗每48小时进行一次.
主要成果:
- 患者在COVID-19后出现了SJS/TEN症状和肝脏内胆固醇症.
- 皮质类固醇治疗没有改善皮肤病变.
- 七次DPMAS治疗导致皮肤症状的逐渐改善和消失.
结论:
- DPMAS疗法是SJS/TEN的有益治疗方法.
- 在DPMAS中,血吸附和 perfusion 技术可以减少关键的炎症介质.
- DPMAS可能会减轻与SJS/TEN病原发生有关的炎症过程.
相关概念视频
Clinical Applications of Epidermal Stem Cells
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Pharmaceutical Poisoning: Treatment Strategies
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...

