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七个人类指数的比较,以预测美国成年人中高血压加上高尿血症的预测
1Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Frontiers in endocrinology
|March 25, 2024
概括
七个人类指数,包括身体圆度指数 (BRI),与高血压和高尿血症 (HTN-HUA) 有显著的关联. BRI显示出对HTN-HUA的非侵入性早期检测有很大的潜力.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征研究 代谢综合征研究
- 生物识别分析 生物识别分析
背景情况:
- 高血压和高尿血 (HTN-HUA) 是心血管疾病的重要危险因素.
- 确定HTN-HUA的可靠指标对于早期干预和管理至关重要.
- 人类指数为代谢和心血管健康提供潜在的非侵入性标记.
研究的目的:
- 为了比较高血压加上高尿血 (HTN-HUA) 与七个人类指数的关联.
- 评估这些指数在识别HTN-HUA的个体中的预测能力.
主要方法:
- 利用来自代表性成年人群的国家健康和营养检查调查 (NHANES) 的数据.
- 使用后勤回归分析来确定相关性和赔率比率 (OR).
- 应用接收器运行特征 (ROC) 曲线来评估指数的预测能力.
主要成果:
- 所有七个人类指数 (AIP,LAP,VAI,TyG,BRI,ABSI,CMI) 都显示出与HTN-HUA的显著关联.
- 脂质积累产品 (LAP) 和BRI表现出显著的区分能力,AUC分别为0.72和0.73.
- 这些指数的最高四分位数表明HTN-HUA的几率增加,LAP (OR 9.52) 和BRI (OR 9.08) 显示最强的关联.
结论:
- 血动脉生成指数 (AIP),脂质积累产物 (LAP),内脏脂肪指数 (VAI),甘油三糖指数 (TyG),身体圆度指数 (BRI),身体形状指数 (ABSI) 和心脏代谢指数 (CMI) 都与HTN-HUA有显著的相关性.
- LAP和BRI在区分HTN-HUA个体方面显示出显著的潜力.
- BRI是HTN-HUA早期检测和管理的一个有价值的,非侵入性的工具.
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