创伤后压力和未来的物质使用结果:利用先前的因素来分层风险
Henri M Garrison-Desany1, Jacquelyn L Meyers2, Sarah D Linnstaedt3
1Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Frontiers in psychiatry
|March 25, 2024
概括
创伤后应激障碍 (PTSD) 与烟草和酒精使用有关,但与大麻无关. 童年创伤和身体健康影响这种关系,指导针对性干预物质使用并发症.
科学领域:
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
- 流行病学 流行病学
背景情况:
- 创伤后应激障碍 (PTSD) 和物质使用障碍 (烟草,酒精,大麻) 经常同时发生.
- 人口统计,心理社会地位,先前的创伤和身体健康等因素会影响这种并发症.
- 研究新物质使用和PTSD相关因素的前性研究是有限的.
研究的目的:
- 为了前性地研究PTSD症状与未来物质使用 (烟草,酒精,大麻) 之间的关系.
- 确定改变PTSD与物质使用之间的关联的关键因素.
- 为患有并发性PTSD和物质使用的个体提供量身定制的干预信息.
主要方法:
- 对2943名急诊室患者进行的前性队列研究 (进一步了解创伤后的康复 - AURORA).
- 在六个时间点评估的自我报告的PTSD症状和物质使用 (频率,数量).
- 波桑概括了用于评估关联的估计方程;因果森林从128个变量中确定了效果修饰者.
主要成果:
- 创伤后应激障碍症状与增加的烟草和酒精使用频率和数量有关.
- 在PTSD和大麻使用之间没有发现显著的关联.
- 终身吸烟,自我评价的身体健康和童年创伤成为显著的调节者.
结论:
- 创伤后应激障碍与烟草和酒精使用有很强的相关性,对大麻的清晰度较低.
- 确定风险分层对于定制干预措施以减轻PTSD和物质使用并发症至关重要.
- 烟草和酒精使用受到PTSD的显著影响,而大麻使用似乎受到的影响较小.
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