相关实验视频
Updated: Jun 29, 2025
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
7.1K
过去二十年中炎症性肠病的演变:一项按时间顺序进行的跨国研究
Pezhman Alavinejad1, Seyed Jalal Hashemi1, Nitin Behl2
1Alimentary Tract Research Centre, Imam Khomeini Hospital Clinical Research Development Unit, The School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
EClinicalMedicine
|March 25, 2024
概括
炎症性肠病 (IBD) 的表现已经发生了变化,性结肠炎现在更倾向于左侧结肠炎,克罗恩病显示上部肠道干预增加. 患者经历的发作较少,肠外疾病也较少.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 内部医学 内部医学
背景情况:
- 炎症性肠病 (IBD) 是多因素的,具有各种各样的个人表现.
- 了解IBD因环境因素而演变的行为对于改善患者的治疗结果至关重要.
研究的目的:
- 调查过去二十年来IBD行为,表现和特征的变化.
- 提高IBD患者的诊断,治疗和治疗结果.
主要方法:
- 一项为期6个月的研究 (2022年2月至7月) 收集了来自6个国家的IBD门诊的数据.
- 根据诊断时间分组患者:>15年前 (A组),5-15年前 (B组) 和<5年前 (C组).
- 普遍存在的IBD亚型和特征被评估,并在各组之间进行比较.
主要成果:
- 其中1430名IBD患者包括84.5%的性结肠炎 (UC),14.3%的克罗恩病 (CD). 诊断时的平均年龄为30岁.
- 与较老的组 (A和B) 相比,最近诊断的肠外干扰减少了 (C组).
- 在C组中,UC亚型从大肠炎转移到左侧大肠炎.CD显示上部GI参与度增加. 食物敏感性和疾病爆发近年来有所减少.
结论:
- 最近IBD的表现,特别是UC,已经发生了显著的变化.
- 在CD中增加上部胃肠道的参与和没有疾病爆发的患者的更高患病率是值得注意的趋势.
- 肠外干扰的减少表明,随着时间的推移,疾病表现的潜在转变.
相关概念视频
01:30Inflammatory Bowel Disease II: Crohn's Disease
233
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
233
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
179
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
179
01:17Chronic Bowel Disorders: Introduction
450
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
450
01:29Inflammatory Bowel Disease IV: Pharmacological Management
127
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
127
01:21Inflammatory Bowel Disease V: Surgical Management
145
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
145