软件变化的影响在澳大利亚第三级急诊室对氧化处方的影响:回顾性审查
Giles Barrington1, Katherine Davis2, Zach Aandahl3
1Royal Hobart Hospital, Tasmanian Health Service, Hobart 7000, Australia.
Pharmacy (Basel, Switzerland)
|March 25, 2024
概括
改变电子处方软件减少了从急诊部 (ED) 发放的氧化即时释放 (IR) 药片数量. 这种基于系统的干预措施通过促使处方者限制阿片类药物处方来支持阿片类药物管理.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 医疗信息学 医疗信息学
背景情况:
- 在急诊室 (ED) 中处方阿片类药物是一个重大的公共卫生问题,原因是广泛的滥用和转移.
- 在ED的挑战包括高患者数量和不可预测的急性呈现,复杂化阿片类药物管理.
- 国家建议主张减少阿片类药物包装尺寸,以减轻危害.
研究的目的:
- 为了评估电子处方软件修改对氧化即时释放 (IR) 处方量的影响.
- 评估系统级变革在促进澳大利亚第三级ED中阿片类药物管理原则的有效性.
主要方法:
- 在两个六个月期间 (2019-2021) 进行了氧化IR处方的回顾性审查.
- 在软件调整之前和之后进行的分析,将自动填充的平板电脑数量从20减少到10.
- 线性混合效应回归建模,结合患者人口统计和处方医生的经验.
主要成果:
- 每份处方中处方的氧化红外线药片的中位数显著减少 (13.5至10.0,p < 0.001).
- 总体上,所处方的氧 IR 药片总数下降了 11.65%.
- 处方经验,患者年龄和患者性别影响了处方大小.
结论:
- 修改电子处方软件的默认设置有效地减少了阿片类药片的数量.
- 基于系统的干预措施可以影响医疗保健提供者的行为,并鼓励遵守阿片类药物管理.
- 这种方法为减少在紧急情况下的阿片类药物处方提供了一个实际的策略.
相关概念视频
Opioid Analgesics: Synthetic and Semisynthetic Opioids
287
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
287
Analgesia and Pain Management
614
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
614
Opioid Analgesics: Morphine and Other Natural Cogeners
244
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
244
Prescription, Nonprescription and Orphan Drugs
725
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
725
Drug Dependence
1.0K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.0K
Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K


