在医疗补助中,抗生素处方的减少和明显的地理变化
Alexia G Aguilar1, Priscilla C Canals1, Maria Tian1
1Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 17822, USA.
Pharmacy (Basel, Switzerland)
|March 25, 2024
概括
抗生素处方总体下降,而宽谱抗生素出现了最大的下降. 美国各州在抗生素处方方面发现了显著的地理差异.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 抗生素耐药性是一个关键的全球健康挑战.
- 了解抗生素处方模式对于抗菌药物管理至关重要.
- 以前的研究表明抗生素使用的差异,但需要对大型数据集进行全面分析.
研究的目的:
- 分析美国抗生素处方的趋势和地理差异.
- 为了比较广谱抗生素与狭谱抗生素的处方率.
- 确定抗生素处方量较高的地区,以便进行潜在的干预.
主要方法:
- 从2013年到2020年的医疗支出小组系统 (MEPS) 中使用的数据.
- 在2018年和2019年,每1000名医疗补助计划注册者抽取了八种常见抗生素 (四种宽谱,四种窄谱) 的处方率.
- 分析了各州处方率的地理差异.
主要成果:
- 从2013年到2020年,MEPS患者的整体抗生素处方减少了38.7%,广谱抗生素的下降更大 (-53.7%).
- 医疗补助的抗生素处方减少了6.7%.
- 观察到显著的地理差异,最高和最低处方州之间的差异是2.8倍,南方的比例高于西方.
结论:
- 抗生素的处方量有所下降,特别是对于广谱药物,但仍然存在很大的地理差异.
- 针对性管理计划可能在门诊抗生素处方率高的地区是有益的.
- 解决地理差异对于在全国范围内有效的抗菌药物管理至关重要.
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