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Damien Scaia¹, Karine Fombellida², Nathalie Maes³

¹Public Health Science Department, University of Liège, 4000 Liège, Belgium.

Infectious disease reports

|March 25, 2024

概括

迟到的艾滋病毒诊断增加了健康风险和传播. 高龄和撒哈拉以南非洲人与晚期艾滋病毒疾病有关,强调需要扩大传统风险组之外的查.

科学领域:

传染性疾病传染性疾病
公共卫生公共卫生
流行病学流行病学

背景情况:

人类免疫缺陷病毒 (HIV) 的晚期诊断与不良健康结果有关,包括增加死亡率,发病率,医疗保健成本和病毒传播.
识别与晚期艾滋病毒呈现相关的因素对于制定有针对性的预防和早期干预策略至关重要.

研究的目的:

确定晚期艾滋病毒呈现 (LPs) 和晚期疾病呈现 (LPs-AD) 的患者比例.
识别与晚期艾滋病毒呈现和晚期疾病相关的个体特征.

主要方法:

来自利日大学医院 (2018年1月 - 2022年12月) 患者数据的回顾性分析.
包括167名出席护理的参与者.
二元逻辑回归模型被用来分析影响迟到呈现的因素.

主要成果:

38.3%的参与者被归类为晚呈现者 (CD4+T细胞计数<350细胞/mm3或艾滋病定义事件).
21.6%是晚期呈现的晚期疾病 (CD4+T细胞数量<200细胞/mm3或艾滋病定义事件).
年龄较大 (在日志转换年龄上的OR:7.5) 和撒哈拉以南非洲原产地 (OR值为0.30和0.25) 与比利时或其他原产地相比,与LP-AD风险增加有关.

结论:

很大一部分患者迟到没有接受艾滋病毒治疗,很大一部分患者的病情已经晚了.
晚期艾滋病毒疾病的危险因素包括年龄较大和特定的种族起源,这表明需要扩大查范围,超越传统的风险群体.
公共卫生战略应侧重于在不同人群中早期检测艾滋病毒,以减轻对健康的负面影响.

关键词:

艾滋病艾滋病艾滋病是什么?艾滋病病毒艾滋病病毒艾滋病病毒先进的艾滋病病毒病毒.延迟的艾滋病毒诊断迟到的呈现方式有关风险因素的风险因素.

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