埃索诺菲尔性食管炎的流行,发病率和表现特征:瑞典西南部22年人口观测研究
J Plate1,2, T Söderbergh1, J Bergqvist3,4
1Department of Otorhinolaryngology Head and Neck Surgery, Region Västra Götaland, NU-Hospital Group, Trollhättan, Sweden.
概括
性食道炎 (EoE) 是一种慢性食道疾病. 这项研究发现,北艾尔夫斯堡县的EoE患病率更高,发病率越来越高,急性食物栓塞是常见的症状,表明诊断延迟.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 性食道炎 (EoE) 是一种慢性食道炎症疾病,影响所有年龄组.
- 症状包括消化不良和急性食物囊阻塞.
- 诊断需要食道功能障碍的症状,并在活检时≥15个乙酸/高功率场 (HPF).
研究的目的:
- 为了确定EoE在瑞典北艾尔夫斯堡县的流行,发病率和表现症状.
- 在10年期间分析EoE诊断的趋势.
- 确定常见的临床表现和潜在的诊断延迟.
主要方法:
- 从2012年到2022年对患者记录的回顾性分析 (EoE的ICD代码).
- 从2000-2022年对食道活检病理学报告的审查.
- 根据诊断标准对患者进行分类:症状和色素细胞计数 (>15/HPF).
主要成果:
- 诊断了409名EoE患者 (379名成年人,30名儿童).
- 患病率:113 / 100,000 人 (成年人127 人,儿童57 人).
- 发病率:7/100,000,显示出一个上升的趋势.
- 46%的成人和11%的儿童出现了急性玻尿管阻塞;51%的成人和22%的儿童患有纤维化.
结论:
- 该地区的EoE患病率高于以前报告的瑞典西南部.
- 增加的发病率可能反映了人们的意识提高,或是EoE病例的真正增加.
- 急性食物栓塞是常见的症状,可能表明EOE的晚期诊断.
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