系统性贝瓦西祖马布治疗复发性呼吸道乳头瘤:一个单一机构的经验
Raymond J So1, Christopher Rayle1, Henry H Joo1
1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.
The Laryngoscope
|March 25, 2024
概括
系统性贝瓦西祖马布有效地减少了复发性呼吸道乳头瘤 (RRP) 的手术. 这种治疗显示出良好的安全性,喉和气管乳头瘤反应最好,尽管肺RRP可能有部分反应.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 复发性呼吸道乳头炎 (RRP) 需要有效的医疗疗法来限制疾病复发.
- 系统性贝瓦西祖马布是一种有前途的RRP辅助疗法,但其采用受到有限的临床经验和最佳实践意识的阻碍.
研究的目的:
- 评估系统性贝瓦齐祖马布在治疗复发性呼吸道乳头瘤 (RRP) 的疗效和安全性.
- 描述系统性贝瓦西祖马布在高等保健学术医疗中心的治疗结果和并发症概况.
主要方法:
- 用系统性贝瓦齐祖马布治疗的RRP患者的回顾性审查.
- 在所有受影响的解剖学子站点记录人口统计和临床特征,成像发现和疾病反应.
主要成果:
- 系统性贝瓦齐祖马布显著降低了喉和气管RRP的发生率.
- 手术频率在治疗后显著下降 (2.5到0.5次手术/年).
- 常见的并发症包括高血压和蛋白尿.
结论:
- 系统性贝瓦西祖马布有效地减少了与RRP相关的手术,并具有可管理的安全性.
- 喉和气管乳头瘤显示了对系统性贝瓦西祖马布的最高反应率.
- 肺部RRP通常会对系统性贝瓦西祖马布表现出部分或稳定的反应.
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