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Updated: Jun 29, 2025

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes
09:47

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes

Published on: May 25, 2018

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在受管制的内膜蛋白解中基质选择标准

Celine Moser1, Nadja Guschtschin-Schmidt1,2, Mara Silber1

  • 1Institute for Biological Interfaces 4, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.

ACS chemical neuroscience
|March 25, 2024
PubMed
概括

研究人员确定了关键的结构动机,这些动机决定了玛分泌酶 (γ-分泌酶) 如何识别其基质,例如粉样蛋白前体蛋白 (APP),这对于阿尔茨海默病研究至关重要. 这些发现提升了对膜内蛋白酶功能的理解.

关键词:
根据ITGB1的规定.内膜蛋白质溶解是一种内膜蛋白质溶解.粉样蛋白前体蛋白质的前体蛋白质是什么没有口,没有口.核磁共振是一种核磁共振.γ-秘密的秘密

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