Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Threats to Biodiversity01:50

Threats to Biodiversity

22.3K
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
22.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Conservation of Small Populations02:04

Conservation of Small Populations

13.1K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
13.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Deleterious mitochondrial heteroplasmy drives high-risk clonal hematopoiesis and hematological malignancy.

medRxiv : the preprint server for health sciences·2026
Same author

Efficient evidence-based genome annotation with EviAnn.

Nature methods·2026
Same author

Testing the reliability of AI-generated protein structures.

bioRxiv : the preprint server for biology·2026
Same author

Facile generation of <i>Hermes</i> insertion mutants in prototrophic <i>Candida glabrata</i> for use in nutrient-limited environments.

Microbiology spectrum·2026
Same author

Outpatient paracentesis for Ovarian Hyperstimulation Syndrome: STOP-OHSS feasibility study and RCT Synopsis.

Health technology assessment (Winchester, England)·2026
Same author

A complete human pancreatic cancer genome.

bioRxiv : the preprint server for biology·2026

相关实验视频

Updated: Jun 29, 2025

Processing the Loblolly Pine PtGen2 cDNA Microarray
07:01

Processing the Loblolly Pine PtGen2 cDNA Microarray

Published on: March 20, 2009

7.4K

一个被威胁的白皮松的基因组序列.

David B Neale1,2, Aleksey V Zimin3, Amy Meltzer3

  • 1Department of Plant Sciences, University of California, Davis, CA 95616, USA.

G3 (Bethesda, Md.)
|March 25, 2024
PubMed
概括

白皮松 (WBP) 的基因组测序为保护提供了一个至关重要的工具. 这种高质量的基因组组件有助于识别抗病基因,这对WBP恢复工作至关重要.

关键词:
松树 (Pinus albicaulis) 是一个葡萄树.标注注释 标注注释针叶树木的树木是什么意思基因组组装组合的基因组.运动精子 (gymnosperm) 是一种精子.白皮松树松树的树皮是白皮松树.

更多相关视频

Author Spotlight: In Vitro Co-Culture System of Pine Shoots and Pinewood Nematode for Studying Host Volatile Response
08:42

Author Spotlight: In Vitro Co-Culture System of Pine Shoots and Pinewood Nematode for Studying Host Volatile Response

Published on: September 27, 2024

739
An Improved Method of RNA Isolation from Loblolly Pine P. taeda L. and Other Conifer Species
08:25

An Improved Method of RNA Isolation from Loblolly Pine P. taeda L. and Other Conifer Species

Published on: February 22, 2010

13.9K

相关实验视频

Last Updated: Jun 29, 2025

Processing the Loblolly Pine PtGen2 cDNA Microarray
07:01

Processing the Loblolly Pine PtGen2 cDNA Microarray

Published on: March 20, 2009

7.4K
Author Spotlight: In Vitro Co-Culture System of Pine Shoots and Pinewood Nematode for Studying Host Volatile Response
08:42

Author Spotlight: In Vitro Co-Culture System of Pine Shoots and Pinewood Nematode for Studying Host Volatile Response

Published on: September 27, 2024

739
An Improved Method of RNA Isolation from Loblolly Pine P. taeda L. and Other Conifer Species
08:25

An Improved Method of RNA Isolation from Loblolly Pine P. taeda L. and Other Conifer Species

Published on: February 22, 2010

13.9K

科学领域:

  • 基因组学就是基因组学.
  • 林业林业 林业 林业 林业
  • 保护生物学 保护生物学

背景情况:

  • 白皮松 (WBP) 受到白松泡生 (WPBR),山松甲虫,野火和气候变化等严重威胁.
  • 西北美洲西部的WBP种群在其自然范围中经历了显著的死亡率.
  • 基因组技术为加速识别WBP恢复的弹性种子来源提供了一个有希望的途径.

研究的目的:

  • 为了生成白皮松 (Pinus albicaulis) 的高质量参考基因组组.
  • 为了促进与抗白松囊生 (WPBR) 和适应气候变化的基因相关的基因的识别.
  • 为改善WBP保护和恢复的基因组资源.

主要方法:

  • 使用Illumina短读 (haploid megagametophyte) 和牛津纳米孔长读 (二倍体针组织) 的混合组装.
  • 深度测序覆盖和多步骤组装方法.
  • 基因组注释以识别蛋白质编码基因和重复内容,重点关注核酸结合的氨酸丰富重复受体 (NLR).

主要成果:

  • 一个全面的WBP基因组组合27.6Gb在92,740contigs和34,716支架,与87.2%在12个染色体.
  • 鉴定了25362个编码蛋白质的基因,其中超过77%的基因组是重复的.
  • 详细描述了三种NLR亚类的特征,与以前基于转录组的评估相比,在识别方面取得了显著的改进.

结论:

  • 高质量的WBP基因组组装和注释代表了WBP研究和保护的重大进步.
  • 该资源将加速识别WPBR耐药性和气候适应性的遗传标记.
  • 能够为这个危物种提供更有效和更具成本效益的恢复策略.