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在老年人中 Sarcopenia 和 Sarcopenic 肥胖和死亡率
Elizabeth Benz1,2,3, Alexandre Pinel1, Christelle Guillet1
1Human Nutrition Unit, Clermont Auvergne University, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Centre de Recherche en Nutrition Humaine, Clermont-Ferrand, France.
麻症和麻性肥胖 (SO) 在老年人中很常见,并增加死亡风险. 使用低肌肉强度进行早期识别,可以帮助识别那些有过早死亡风险的人.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 麻症和肥胖症是老年人群的全球健康问题.
- 有限证据证实了sarcopenic肥胖 (SO) 的患病率及其与死亡率的联系.
研究的目的:
- 为了确定萨科佩尼亚和SO的流行率.
- 调查萨科佩尼亚,SO和全因死亡率之间的关联.
主要方法:
- 进行了一项基于人口的大规模队列研究 (罗德丹研究).
- 用手握强度和身体构成 (BC) 标准来定义萨科佩尼亚和SO.
- 统计分析包括卡普兰-梅尔曲线和考克斯比例危险回归模型.
主要成果:
- 患病率:11.1%可能的肉病,2.2%确定的肉病,5.0%具有一个改变的BC成分的SO,0.8%具有两个改变的BC成分的SO.
- 死亡风险:可能的肉眼 (HR 1.29) 确认的肉眼 (HR 1.93).
- SO显著增加死亡风险 (HR 1.94-2.84),特别是更改变的BC组件,独立于年龄,性别和BMI.
结论:
- 麻症和SO在老年人中很普遍,并且与所有原因死亡率的增加有关.
- 身体组成的变化会增加死亡风险.
- 低肌肉力量可以帮助早期识别有风险的个体.
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