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Updated: Jun 29, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
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Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

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髓寡细胞 糖蛋白抗体 疾病 视神经炎:一个结构功能悖论?

Ruby Ross1, Rachel Kenney, Laura J Balcer

  • 1Department of Neurology (RR, RK, LJB, SLG, LK, KAON, SNG), Department of Population Health (RK, LJB), and Department of Ophthalmology (LJB, SLG), New York University Grossman School of Medicine, New York, New York.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
|March 25, 2024
PubMed
概括

儿科骨髓寡基细胞糖蛋白抗体疾病 (MOGAD) 导致视神经炎 (ON) 与RNFL稀释,但保持视力敏. 对比度敏感性和色彩视觉缺陷表明MOGAD可能更像MS而不是NMO.

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High-throughput Flow Cytometry Cell-based Assay to Detect Antibodies to N-Methyl-D-aspartate Receptor or Dopamine-2 Receptor in Human Serum

Published on: November 23, 2013

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Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies10:47

Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies

Published on: October 27, 2016

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相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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Nervous Tissue: Myelin01:25

Nervous Tissue: Myelin

The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
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