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在毛病病的小鼠模型中,TMEM106B编码变体具有保护性,删除有害

George A Edwards1, Caleb A Wood1, Yang He2,3

  • 1Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM295, Houston, TX, 77030, USA.

Acta neuropathologica
|March 25, 2024
PubMed
概括

超膜蛋白106B (TMEM106B) 的删除会使毛病症恶化,而一种特定的TMEM106B变体提供神经保护. 这项研究澄清了TMEM106B.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.认知性 认知性在前性痴呆症.鼠标模型模型神经退行发生神经退行.在TMEM106B中使用.塔乌·塔乌 (Tau Tau) 是一个病症是一种病症.

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