机器学习辅助搜索P2Y6和其他P2Y受体的配体

Ana C Puhl1, Sarah A Lewicki2, Zhan-Guo Gao2

  • 1Collaborations Pharmaceuticals, Inc, 840 Main Campus Drive, Lab 3510, Raleigh, NC, 27606, USA.

Purinergic signalling
|March 25, 2024
PubMed
概括

机器学习发现了P2Y6受体的新对手,P2Y6受体是各种疾病的目标. 该研究选了化合物,揭示了ABBV-744作为一种非竞争性的P2Y6R抑制剂,对其他P2YR亚型具有多种影响.

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