三种超声波技术对肝纤维化病阶段的比较研究
Qianqian Shen1,2, Jiaqi Zhang1,2, Shangjie Yang1,2
1Department of Medical Imaging, Shanxi Medical University.
European journal of gastroenterology & hepatology
|March 25, 2024
概括
视觉暂时弹性图 (ViTE) 在确定肝纤维化阶段时显示出高准确度,与高级阶段的声音触摸弹性图 (STE) 和声音触摸量化 (STQ) 相比. 在识别轻度慢性肝病 (CLD) 方面,ViTE优越.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
- 诊断技术 诊断技术 诊断技术
背景情况:
- 肝纤维化分期对于管理慢性肝病 (CLD) 至关重要.
- 过渡性弹性图 (TE) 是一种标准的非侵入性方法.
- 评估较新的弹性图技术以提高精度至关重要.
研究的目的:
- 评估视觉短暂弹性图 (ViTE),声触摸弹性图 (STE) 和声触摸量化 (STQ) 对于肝纤维化病阶段的一致性和性能.
- 将这些方法与暂时弹性图 (TE) 作为黄金标准进行比较.
- 在纤维化评估中确定ViTE,STE和STQ的最佳切线.
主要方法:
- 同时对252名CLD患者进行TE,ViTE,STE和STQ检查.
- 进行了相关性和协议分析.
- 用接收器操作特征 (ROC) 曲线来评估诊断性能和确定最佳的切断点.
主要成果:
- ViTE与TE (r=0.863) 显示出强烈的相关性,表现优于STE (r=0.709) 和STQ (r=0.727).
- 所有方法的总体一致性 (ICC) 高 (0.911).
- 对于检测较低的纤维化阶段 (TE≥5 kPa和≥10 kPa),ViTE显示的AUROC明显高于STE和STQ,而对于高级阶段 (TE≥15 kPa和≥20 kPa),性能可比.
结论:
- ViTE,STE和STQ对肝纤维化阶段表现出很好的相关性和一致性.
- 在识别轻微的CLD阶段和有效排除补偿的高级CLD方面,ViTE比STE和STQ更准确.
- ViTE为肝纤维化评估提供了一种有价值的替代方案,特别是在区分早期疾病时.
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