没有1的药物
Peter Wang1,2,3, Qiao Ying Leong1,2, Ni Yin Lau1,2
1Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Singapore medical journal
|March 25, 2024
概括
精准医学通过为个体量身定制护理来推进治疗. 这篇文章探讨了数字健康和N-of-1医学的个性化组合疗法和剂量,旨在加速临床实践的变化.
科学领域:
- 生物医学信息学 生物医学信息学
- 翻译医学是一种翻译医学.
- 药物基因组学 药物基因组学
背景情况:
- 精准医学和个性化医学提供基于个体患者数据的量身定制治疗.
- 方法包括基因组引导的药物选择,单一患者基因疗法和基于协同作用的药物组合.
- 不同的建议需要明确定义和区分这些领域.
研究的目的:
- 定义和区分精准医学,个性化医学和相关领域.
- 探索数字健康和数字医学在推进N-of-1医学的作用.
- 为开发新的工作流程和临床试验设计提供建议.
主要方法:
- 关于数字健康和数字医学的概念阐述. 支持N-of-1医学.
- 审查精准和个性化医学的现有方法.
- 讨论临床试验设计,工作流程开发和监管方面的影响.
主要成果:
- 通过数字平台实现的N-of-1药物,通过患者特定数据来个性化组合疗程和剂量.
- 在精准和个性化医疗中认识到多样性,加速了工作流程的发展.
- 数字健康整合是推进个性化治疗策略的关键.
结论:
- 清晰的定义和区分对于推进精确和个性化医学的发展至关重要.
- 数字健康和N-of-1医疗是迈向高度个性化的患者护理的重要一步.
- 提供了关于开发未来医学数字化平台和工作流程的建议.
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