使用Buchanania obovata水果提取物和以欧特克为基础的离子液体的ZnO纳米颗粒的生物合成和抗菌活性
Kadhim Qasim Jabbar1, Azeez Abdullah Barzinjy2,3
1Department of Physics, College of Education, Salahaddin University-Erbil, Kurdistan Region, Iraq.
Nanotechnology
|March 25, 2024
概括
这项研究使用水果提取物和离子液合成了氧化纳米粒子 (ZnO NPs). 离子液体方法产生了ZnONP,它们对大肠杆菌和金黄色杆菌具有优越的抗菌活性.
科学领域:
- 绿色化学和纳米技术
- 材料科学与工程 材料科学与工程
- 生物技术和微生物学
背景情况:
- 开发环境友好和成本效益高的纳米粒子合成方法至关重要.
- 氧化纳米颗粒 (ZnO NPs) 具有显著的抗菌特性.
- 解决抗生素耐药性的问题需要探索新的治疗药物.
研究的目的:
- 使用布卡纳尼亚果实提取物和基于欧的离子液体生物合成氧化纳米颗粒 (ZnO NPs).
- 研究合成的 ZnO NPs 的结构,光学和形态特性.
- 评估生物合成的ZnONP对格拉姆阴性 (大肠杆菌) 和格拉姆阳性 (黄金杆菌) 细菌的抗菌功效.
主要方法:
- 绿色合成的ZnONP使用布卡纳尼亚obovata水果提取物和eutectic-based离子液体.
- 使用表面等离子共振 (SPR),X射线衍射 (XRD),扫描电子显微镜 (SEM),传输电子显微镜 (TEM) 和布鲁纳uer-Emmett-Teller (BET) 分析对 ZnO NP 的表征.
- 通过抑制区方法对大肠杆菌和金黄色杆菌的临床分离物进行抗菌活性评估.
主要成果:
- 通过SPR在340nm (水果提取物) 和320nm (离子液体) 的峰值证实了 ZnO NPs的成功合成.
- 通过XRD检测证实了ZnONP的石六角结构.
- SEM和TEM揭示了大约40nm (果实提取物) 和25nm (离子液体) 的六角晶体ZnONP.
- BET分析显示表面积为~13 m2g-1 (水果提取物) 和~29 m2g-1 (离子液体).
- 使用以欧特基为基础的离子液合成的 ZnO NPs 与以水果提取物为媒介的 ZnO NPs 相比,对 S. aureus (16 mm 抑制区) 和 E. coli (1000 度的 15 mm 抑制区) 均表现出优越的抗菌活性.
结论:
- 生物合成的ZnONP为传统化学药物提供了一个有希望的,环保的替代品.
- 基于eutectic的离子液体方法在合成具有增强抗菌性能的ZnONP方面更有效.
- 这些发现有助于开发用于打击耐药细菌感染的新策略.
关键词:
布卡纳尼亚奥博瓦塔 (Buchanania obovata) 是一个大的植物.这是ZnO纳米粒子.它具有抗菌活性,具有抗菌活性.基于eutectic 的离子液体.果实提取物 果实提取物绿色合成是一种绿色合成.更多相关视频
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